John Wayne Casserole

I’ve made this casserole several times now, and it is always a hit. Named after western film star, John Wayne, it is reminiscent of chuck wagon food. It is great for groups of meat and cheese lovers. It seems every time that I make it a little differently. I have managed to stretch one pound of meat and one tomato into a decent casserole when supplies were running low. Recently, however, my mother had the idea to change the original two pounds of beef into one pound pork and one pound beef. That was the winning combo.

The trickiest part of preparing this casserole is the layers. To start with, mix your two cups of Bisquick with one cup water until dough forms. Spread that in the bottom of the pan. Don’t worry if it is thin in places or doesn’t reach the edges. Once it rises, everything will be smoothed out.biscuit doughNext, add in everything you’ve sautéed. If you mixed your meat, peppers, and onions, add them together. If, like me, you didn’t have enough room in your pan, add the meat first, then the peppers and onions.meatpeppers and onionsNow layer on your beautiful sliced tomatoes.tomatoesYou want to add the sour crème mixture now. It will make everything all creaming and delicious. Then top with shredded cheese and bake!cream mixturecheese

‘John Wayne Casserole’

Source: Adapted from Mississippi Magazine


1 pound ground beef, cooked and drained

1 pound ground pork, browned

1 (1.25-ounce) packet taco seasoning or cumin, cayenne pepper, and garlic powder

4 ounces sour cream

4 ounces mayonnaise

8 ounces Cheddar cheese, shredded and divided

1 yellow onion, chopped

2 cups Bisquick

1 cup of water

2 tomatoes, sliced

1 green bell pepper, chopped


  1. Heat oven to 325. Brown ground beef and pork and add taco seasoning, set aside.
  1. In a separate bowl, combine sour cream, mayonnaise, 4 ounces of cheddar cheese, and half of the onions; set aside.
  1. Stir Bisquick and water together to form soft dough. Pat dough on the bottom and one-half-inch up the sides of an 9 x 13 in greased casserole dish.
  1. Saute remaining onions and bell peppers until slightly tender.
  1. On top of biscuit mix, evenly distribute ingredients in the following order: ground beef, tomato slices, green peppers, onions, jalapeno peppers, sour cream mixture and end with remaining shredded cheese.
  1. Bake for 30-40 minutes or until edges of dough are lightly browned.

There you have it: a yummy casserole for the cowboys and girls in your life.


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